Recombinant Human CD79a Protein

重组人CD79a蛋白 | 重组人 CD79a 蛋白

CD79a antigen | CD79a molecule, immunoglobulin-associated alpha | CD79A | IGAB-cell antigen receptor complex-associated protein alpha chain | ig-alpha | MB-1 membrane glycoprotein | MB1 | MB-1 | Membrane-bound immunoglobulin-associated protein | Surface I

rp181593-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Protein Function: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B cells.

重组表达

13.3 kDa

C-His

27.0-49.0 kDa, under reducing conditions

HEK293 Accession #: P11912 | HEK293

<1.0 EU/μg

人(Human)

1-143 aa

MPGGPGVLQALPATIFLLFLLSAVYLGPGCQALWMHKVPASLMVSLGEDAHFQCPHNSSNNANVTWWRVLHGNYTWPPEFLGPGEDPNGTLIIQNVNKSHGGIYVCRVQEGNESYQQSCGTYLRVRQPPPRPFLDMGEGTKNRHHHHHH

Yes

Yes