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Product details

名称

Recombinant Human CD81 Protein

别名

重组人CD81蛋白 | 重组人四次跨膜CD81蛋白

英文别名

货号

rp181595-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

生化机理

CD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition. Post-translational: Not glycosylated. Likely constitutively palmitoylated at low levels. Protein palmitoylation is up-regulated upon coligation of BCR and CD9-C2R-CD81 complexes in lipid rafts.

生物活性

Testing in progress

来源

重组表达

预测分子量

10.6 kDa

蛋白标签

N-His

SDS-PAGE

10.0 kDa, under reducing conditions; 10.2 kDa, under non-reducing conditions.

表达系统

HEK293 Accession #: P60033 | HEK293

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

113-201 aa

序列

HHHHHHFVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHETLDCCGSSTLTALTTSVLKNNLCPSGSNIISNLFKEDCHQKIDDLFSGK

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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