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Product details

名称

Recombinant Human Ephrin-A5 Protein

别名

重组人Ephrin-A5蛋白 | 重组人肾上腺素A5蛋白 | 重组人肝配蛋白A5 | 重组人AL-1蛋白

英文别名

货号

rp183615-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

生化机理

Ephrin-A5 also known as EFNA5, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. Ephrin-A5/EFNA5 may function actively to stimulate axon fasciculation. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Ephrin-A5/EFNA5 also serves as a cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.

生物活性

Immobilized Recombinant Human Ephrin-A5 Protein (rp183615) at 1.0 μg/mL can bind Recombinant Human EphA4 Protein (rp183616) with the EC50 of 175.1 ng/mL.

来源

重组表达

预测分子量

22.0 kDa

蛋白标签

C-His

SDS-PAGE

26.0 kDa, under reducing conditions; 25.1 kDa, under non-reducing conditions.

表达系统

HEK293 Accession #: P52803 | HEK293

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

1-203 aa

序列

MLHVEMLTLVFLVLWMCVFSQDPGSKAVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVHDRVFDVNDKVENSLEPADDTVHESAEPSRGENHHHHHH

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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