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Product details
名称
Recombinant Human VSIG3 Protein
别名
重组人VSIG3蛋白 | 重组人免疫球蛋白超家族成员11 | 重组人 VSIG3 蛋白
英文别名
Brain and testis-specific immunoglobulin superfamily protein | BTIGSF | BT-IgSF | cancer/testis antigen 119 | CT119 | CXADR like 1 | CXADRL1 | IGSF11 | Igsf13 | immunoglobulin superfamily member 11 | immunoglobulin superfamily, member 11 | MGC35227 | V-se
货号
rp183625-10μg
包装规格
10μg
级别
无动物源
浓度
≥90%(SDS-PAGE)
生化机理
VSIG3 又称 IGSF11、BT-IgSF 和 CLMP,是一种约 50 kDa 的跨膜粘附蛋白。成熟的人类 VSIG3 由一个 219 氨基酸(aa)的胞外结构域(ECD)组成,其中包含两个串联的 Ig 样结构域、一个 21 aa 的跨膜区段和一个 169 aa 的胞质部结构域。在 ECD 中,人 VSIG3 与小鼠和大鼠 VSIG3 有 95% 的 aa 序列相同。替代剪接产生了具有替代信号肽的其他异构体,这些异构体的第二个 Ig 样结构域可能也有缺失。VSIG3 表达于上皮细胞、内皮细胞、神经元、神经胶质细胞和血小板。它定位在上皮细胞的紧密连接处,并介导同亲性的跨细胞粘附。VSIG3 还能定位到神经元突触后的突触部位,在那里它能招募 AMPA 受体的 GluA1 和 GluA2 亚基,支持兴奋性突触传递。在胃癌中,短同工酶可上调。在斑马鱼中,VSIG3 在黑色素细胞及其前体中表达,在色素细胞的发育和模式化过程中发挥作用。 翻译后:N-糖基化。
生物活性
Testing in progress
来源
重组表达
预测分子量
24.4 kDa
蛋白标签
C-His
SDS-PAGE
30.6-37.3 kDa, under reducing conditions; 28.9-35.2 kDa, under non-reducing conditions
表达系统
HEK293 Accession #: Q5DX21 | HEK293
内毒素水平
<1.0 EU/μg
种属
人(Human)
氨基酸
1-245 aa
序列
MTSQRSPLAPLLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGHHHHHH
无动物源
Yes
无载体
Yes
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
Articles
「No related articles yet」
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Research chemical ≥90%

Research chemical ≥90%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥90%.

item number:rp183625-10μg
Product model:10μg
level: ≥90%
Lead Time:30days
sold 11 Items
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10μg

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