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Product details

名称

Recombinant Human S100A9 Protein

别名

重组人S100A9蛋白 | 重组人S100A9蛋白

英文别名

货号

rp183637-10μg

包装规格

10μg

级别

无载体

浓度

≥95%(SDS-PAGE)

产品介绍

Protein Function: Calcium-binding protein. Has antimicrobial activity towards bacteria and fungi. Important for resistance to invasion by pathogenic bacteria. Up-regulates transcription of genes that are under the control of NF-kappa-B. Plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS) (By similarity). Promotes tubulin polymerization when unphosphorylated. Promotes phagocyte migration and infiltration of granulocytes at sites of wounding. Plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1. Extracellular calprotectin binds to target cells and promotes apoptosis. Antimicrobial and proapoptotic activity is inhibited by zinc ions.

生物活性

1. Immobilized Recombinant Human S100A8 Protein (rp183594) at 2.0 μg/mL can bind Recombinant Human S100A9 Protein (rp183637) with the EC50 of 135.5 ng/mL. 2. Immobilized Recombinant Human S100A9 Protein (rp183637) at 2.0 μg/mL can bind Recombinant Human S100A8 Protein (rp183594) with the EC50 of 194.6 ng/mL.

来源

重组表达

预测分子量

14.0 kDa

蛋白标签

C-His

SDS-PAGE

12.7 & 28.7 kDa, under reducing conditions; 12.7 & 28.7 kDa, under non-reducing conditions

表达系统

E. coli Accession #: P06702 | E. coli

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

1-114 aa

序列

MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTPHHHHHH

无动物源

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

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