Recombinant Human Carbonic Anhydrase II Protein

重组人Carbonic anhydrase 2蛋白 | 重组人碳酸酶2蛋白

CA2 | CAII | CA-IIEC 4.2.1.1 | Car2 | Carbonate dehydratase II | carbonic anhydrase 2 | carbonic anhydrase B | Carbonic anhydrase C | Carbonic Anhydrase II | carbonic anhydrase IICAC | carbonic dehydratase

rp183662-10μg

10μg

无载体

≥90%(SDS-PAGE)

Carbonic Anhydrase (CA) catalyzes the reversible reaction of CO2 + H2O = HCO3- + H+, which is fundamental to many processes such as respiration, renal tubular acidification, and bone resorption. Topics in the CA meeting (6th International Conference on the CAs, June 20‑25, 2003, Slovakia) ranged from use of CAs as markers for tumor and hypoxia in the clinic, as nutritional supplement in milk, and as a tool for CO2 removal and mosquito control in industry. CA2 is a cytosolic enzyme with the highest activity among all known CAs. Mutations in the CA2 gene result in the CA II deficiency syndrome, an autosomal recessive disorder that produces osteopetrosis, renal tubular acidosis, and cerebral calcification.

Measured by its esterase activity. The specific activity is >100 pmol/min/µg, as measured under the described conditions.

重组表达

30.6 kDa

C-10His

29.2 kDa, under reducing conditions; 29.2 kDa, under non-reducing conditions.

E. coli Accession #: P00918 | E. coli

<1.0 EU/μg

人(Human)

1-260 aa

MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFKHHHHHHHHHH

No

Yes