Recombinant Human SULT2B1 Protein

重组人SULT2B1蛋白 | 重组人磺基转移酶家族2B成员1蛋白

Alcohol sulfotransferase | Cytosolic Sulfotransferase 2B1 | EC 2.8.2 | EC 2.8.2.2 | HSST2 | HSST2sulfotransferase family cytosolic 2B member 1 | Hydroxysteroid sulfotransferase 2 | ST2B1 | Sulfotransferase 2B1 | sulfotransferase family, cytosolic, 2B, mem

rp183709-10μg

10μg

无载体

≥90%(SDS-PAGE)

Sulfotransferase family cytosolic 2B member 1, also known as Sulfotransferase 2B1, ST2B1, Alcohol sulfotransferase, Hydroxysteroid sulfotransferase 2, SULT2B1 and HSST2, is a cytoplasm protein that belongs to the sulfotransferase 1 family. The human hydroxysteroid sulfotransferase (SULT) family is comprised of two subfamilies, SULT2A1 and SULT2B1. SULT2B1 is expressed highly in placenta, prostate and trachea. A lesser expression of SULT1B1 was observed in the small intestine and lung. SULT2B1 catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. SULT2B1 sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol. The two SULT2B1 isoforms, SULT2B1a and SULT2B1b, are encoded by a single gene as a result of alternative transcription initiation and alternative splicing. SULT2B1b catalyzes the sulfonation of 3beta-hydroxysteroid hormones and cholesterol, whereas SULT2B1a preferentially catalyzes pregnenolone sulfonation. Post-translational: Phosphorylated.

Immobilized Recombinant Human SULT2B1 Protein (rp183709) at 1.0 μg/mL can bind SULT2B1 Mouse mAb (Ab129738) with the EC50 of 86.8 ng/mL.

重组表达

35.5 kDa

No tag

32.2 kDa, under reducing conditions; 32.2 & 62.7 kDa, under non-reducing conditions.

E. coli Accession #: O00204 | E. coli

<1.0 EU/μg

人(Human)

2-311 aa

GDGPAEPQIPGLWDTYEDDISEISQKLPGEYFRYKGVPFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGTTWMIEIICLILKEGDPSWIRSVPIWERAPWCETIVGAFSLPDQYSPRLMSSHLPIQIFTKAFFSSKAKVIYMGRNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDHIKGWLRMKGKDNFLFITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKANTMSNYTLLPPSLLDHRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQMRGMPTFPWDE

No

Yes