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名称
Recombinant Human Ube2H Protein
别名
重组人Ube2H蛋白 | 重组人Ube2H蛋白
英文别名
E2 20K | GID complex subunit 3 UBC8 homolog | GID3 | Ubc H2 | UBC8 | UBCH | UBCH 2 | UBCH2 | Ube2h | UBE2H_HUMAN | Ubiquitin carrier protein H | Ubiquitin conjugating enzyme E2 H | Ubiquitin conjugating enzyme E2H | Ubiquitin conjugating enzyme E2H (UBC8
货号
rp183711-10μg
包装规格
10μg
级别
无载体
浓度
≥95%(SDS-PAGE)
生化机理
UBE2H 是泛素结合 E2 家族的成员,其成员执行泛素化反应的第二步。泛素化最初被认为是蛋白质降解的主要过程,但如今人们认为泛素化对更广泛的细胞过程至关重要。泛素连接反应的结果以及底物的命运在很大程度上取决于所连接的泛素分子的数量以及这些泛素分子的相互连接方式。为了应对这种复杂性,并在时间和空间上实现充分的泛素化,人们开发了一种高度复杂的连接机制。泛素被泛素激活酶(E1)激活,然后将泛素转移到一组泛素结合酶(E2)上。接下来,载入泛素的 E2 与泛素蛋白连接酶(E3)相互作用,泛素被 E3 招募后与底物结合。这三种关键酶在一个分级系统中运作,目前已发现 2 个 E1 和 35 个 E2,在人类中已发现数百个 E3。
生物活性
Testing in progress
来源
重组表达
预测分子量
21.4 kDa
蛋白标签
N-His
SDS-PAGE
20.6 kDa, under reducing conditions; 20.6 kDa, under non-reducing conditions
表达系统
E. coli Accession #: P62256 | E. coli
内毒素水平
<1.0 EU/μg
种属
人(Human)
氨基酸
2-183 aa
序列
MHHHHHHSSPSPGKRRMDTDVVKLIESKHEVTILGGLNEFVVKFYGPQGTPYEGGVWKVRVDLPDKYPFKSPSIGFMNKIFHPNIDEASGTVCLDVINQTWTALYDLTNIFESFLPQLLAYPNPIDPLNGDAAAMYLHRPEEYKQKIKEYIQKYATEEALKEQEEGTGDSSSESSMSDFSEDEAQDMEL
无动物源
No
无载体
Yes
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
Articles
「No related articles yet」
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Research chemical ≥95%

Research chemical ≥95%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥95%.

item number:rp183711-10μg
Product model:10μg
level: ≥95%
Lead Time:30days
sold 890 Items
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