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Product details

名称

Recombinant Human Aminopeptidase N/CD13 Protein

别名

重组人Aminopeptidase N/CD1蛋白 | 重组人氨基肽酶N蛋白 | 重组人分化簇13蛋白

英文别名

alanyl (membrane) aminopeptidase | Alanyl aminopeptidase | Aminopeptidase M | Aminopeptidase N | ANPEP | AP-M | APN | AP-N | CD13 antigen | CD13 | CD13APN | EC 3.4.11 | EC 3.4.11.2 | gp150 | LAP1 | Microsomal aminopeptidase | Myeloid plasma membrane glyco

货号

rp183728-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

生化机理

The human ANPEP gene encodes aminopeptidase N (APN), which is also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161. The deduced amino acid sequence of human APN consists of a short cytoplasmic tail (residues 2 to 8), a transmembrane region (residue 9 to 32), a Ser/Thr rich region and a zinc metalloprotease domain (residues 69 to 966). Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. The roles of APN in many fields, such as neuroscience, hematopoietic cells, immune system, angiogenesis, cancer and viral infection, have been reviewed. Post-translational: Sulfated. N- and O-glycosylated. May undergo proteolysis and give rise to a soluble form.

生物活性

Immobilized Recombinant Human Aminopeptidase N/CD13 Protein (rp183728) at 1.0 μg/mL can bind Recombinant CD13 Antibody (Ab093779) with the EC50 of 10.7 ng/mL.

来源

重组表达

预测分子量

104.1 kDa

蛋白标签

C-10His

SDS-PAGE

116.7-143.9 kDa, under reducing conditions; 112.4-136.7 kDa, under non-reducing conditions.

表达系统

CHO Accession #: P15144 | CHO

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

69-967 aa

序列

KAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWFTENSKHHHHHHHHHH

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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