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Product details

名称

Recombinant Human CD90/Thy1 Protein

别名

Thy1 | 重组人CD90/Thy1蛋白 | 重组人 CD90/Thy1 蛋白

英文别名

货号

rp183754-50μg

包装规格

50μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

产品介绍

Purity: ≥95%, by SDS-PAGE visualized with Coomassie® Blue Staining Description: CD90, also known as Thy1, is an approximately 25-35 kDa glycoprotein that mediates cellular adhesion and exerts wide-ranging effects in different tissues. CD90 is expressed on hematopoietic progenitor cells, neurons, and activated vascular endothelial cells. Its species-specific expression in lymphoid cells allows its use as a thymocyte and pan T cell marker in mice but not in humans. CD90 can form dimers and higher-order multimers. It binds to heparin, the proteoglycan Syndecan-4, and Integrins alpha M beta 2, alpha V beta 3, and alpha V beta 5. Through these interactions, CD90 inhibits neurite outgrowth, promotes astrocyte adhesion, mediates the adhesion and extravasation of leukocytes and melanoma cells, supports Thrombospondin-1-induced disassembly of fibroblast focal adhesions, and inhibits the activation of latent TGF-beta 1, myofibroblast differentiation, and lung fibrosis. Human Thy-1 shares 63% and 66% amino acid similarity with mouse and rat homologs.

生物活性

Immobilized Recombinant Human CD90/Thy1 Protein (rp183754) at 2.0 μg/mL can bind CD90/Thy1 Mouse mAb (Ab095497) with the EC50 of 287.4 ng/mL.

来源

重组表达

预测分子量

13.4 kDa

蛋白标签

C-His

SDS-PAGE

16.8-33.2 kDa, under reducing condition; 16.8-33.2 kDa, under non-reducing condition

表达系统

HEK293 Accession #: P04216 | HEK293

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

1-130 aa

序列

MNLAISIALLLTVLQVSRGQKVTSLTACLVDQSLRLDCRHENTSSSPIQYEFSLTRETKKHVLFGTVGVPEHTYRSRTNFTSKYNMKVLYLSAFTSKDEGTYTCALHHSGHSPPISSQNVTVLRDKLVKCHHHHHH

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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