Recombinant Human LOX-1/OLR1 Protein

重组人LOX-1/OLR1蛋白 | 重组人 LOX-1/OLR1 蛋白

CLEC8ASLOX1 | CLEC8A | C-type lectin domain family 8 member A | hLOX-1 | Lectin-like oxidized LDL receptor 1 | Lectin-like oxLDL receptor 1 | Lectin-type oxidized LDL receptor 1 | LOX1 | LOX-1 | LOX1ox LDL receptor 1 | LOXIN | OLR1 | oxidised low density

rp184071-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-ligand receptor originally identified as the endothelial oxidized LDL receptor. OLR1 / LOX1 was isolated from an aortic endothelial cell, and recently it has been discovered in macrophages and vascular smooth muscle cells in artery vessels. The expression of LOX1 is induced by inflammatory stimuli and oxidative stimuli. This protein binds, internalizes, and degrades oxidized low-density lipoprotein. LOX1 may play an important role in the progression of vulnerable carotid plaque and might regulate vulnerable plaque formation in cooperation with MMPs and TIMP-2. In clinical, LOX1 is thought to be involved in the development of atherosclerotic lesions.

Testing in progress

重组表达

25.6 kDa

N-His

30.0-38.0 kDa, under reducing conditions; 56.5-68.1 kDa, under non-reducing conditions

HEK293 Accession #: P78380 | HEK293

<1.0 EU/μg

人(Human)

61-273 aa

HHHHHHHHHSQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQMELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLLKINSTADLDFIQQAISYSSFPFWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGAVSQTYPSGTCAYIQRGAVYAENCILAAFSICQKKANLRAQ

Yes

Yes