Recombinant Human FABP4 Protein

重组人FABP4蛋白 | 重组人脂肪酸结合蛋白4蛋白

3T3-L1 lipid-binding protein | 422/aP2 | A-FABP | Adipocyte | Adipocyte lipid binding protein | Adipocyte lipid-binding protein | Adipocyte protein AP2 | Adipocyte-type fatty acid-binding protein | AFABP | ALBP | ALBP/Ap2 | aP2 | Epididymis secretory prot

rp184123-10μg

10μg

无载体

≥95%(SDS-PAGE)

Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. Patients in the highest quartile of FABP4 presented a six-fold increased odds ratio for MS and a three-fold increased odds for LD, adjusted by age, sex, body-mass index and the antiretroviral therapy. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients.

重组表达

15.5 kDa

N-His

13.1 kDa, under reducing conditions; 12.9 kDa, under non-reducing conditions.

E. coli Accession #: P15090 | E. coli

<1.0 EU/μg

人(Human)

2-132 aa

MHHHHHHCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA

No

Yes