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Product details
名称
Recombinant Human Caspase-9 Protein
别名
重组人Caspase-9蛋白
英文别名
APAF-3 | APAF3 | Apoptosis related cysteine peptidase | Apoptotic protease Mch-6 | Apoptotic protease-activating factor 3 | CASP-9 | CASP9 | CASP9_HUMAN | Caspase 9 apoptosis related cysteine peptidase | Caspase 9 Dominant Negative | Caspase 9c | Caspase-
货号
rp184860-10μg
包装规格
10μg
级别
无载体
浓度
≥90%(SDS-PAGE)
生化机理
参与负责执行细胞凋亡的 caspase 的活化级联。caspase-9 与 Apaf-1 结合会导致蛋白酶的激活,然后蛋白酶会裂解并激活效应caspase-3(CASP3)或caspase-7(CASP7)。以 ABL1/c-Abl 依赖性方式促进 DNA 损伤诱导的细胞凋亡。蛋白水解聚(ADP-核糖)聚合酶(PARP)。 翻译后:颗粒酶 B 在 Asp-315 处和 Caspase-3 在 Asp-330 处的裂解产生两个活性亚基。Caspase-8 和 -10 也可参与这些处理过程。
生物活性
Testing in progress
来源
重组表达
预测分子量
32.3 kDa
蛋白标签
N-His & C-His
SDS-PAGE
18.3 & 31.4 kDa, under reducing conditions; 18.3 & 31.4 kDa, under non-reducing conditions.
表达系统
E. coli Accession #: P55211 | E. coli
内毒素水平
<1.0 EU/μg
种属
人(Human)
氨基酸
139-416 aa
序列
MHHHHHHVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTSHHHHHH
无动物源
No
无载体
Yes
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
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「No related articles yet」
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Research chemical ≥90%

Research chemical ≥90%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥90%.

item number:rp184860-10μg
Product model:10μg
level: ≥90%
Lead Time:30days
sold 172 Items
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10μg

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