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Product details

名称

Recombinant Human AMPK alpha 1 Protein

别名

重组人AMPK alpha 1蛋白 | 重组人类 AMPK alpha 1 蛋白

英文别名

货号

rp184863-10μg

包装规格

10μg

级别

无载体

浓度

≥90%(SDS-PAGE)

产品介绍

Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.

来源

重组表达

预测分子量

24.9 kDa

蛋白标签

N-His

SDS-PAGE

28.8 & 54.8 kDa, under reducing conditions; 29.6 & 54.5 kDa, under non-reducing conditions

表达系统

E. coli Accession #: Q13131 | E. coli

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

349-559 aa

序列

MHHHHHHKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ

无动物源

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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