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Product details

名称

Recombinant Human Glyoxalase II Protein

别名

重组人Glyoxalase II蛋白 | 重组人GLO2蛋白 | 重组人乙二醛酶 II 蛋白

英文别名

货号

rp184907-10μg

包装规格

10μg

级别

无载体

浓度

≥95%(SDS-PAGE)

生化机理

HAGH（羟基乙酰谷胱甘肽水解酶）是一个蛋白质编码基因。据报道，人类同工酶有 3 种不同的剪接方式和不同的起始方式。该基因编码的酶被归类为硫酯酶，负责将 S-乳酰谷胱甘肽水解为还原型谷胱甘肽和 D-乳酸。HAGH 属于金属-β-内酰胺酶超家族。HAGH 在肾脏、肝脏和其他组织中广泛表达。与 HAGH 相关的疾病包括羟基乙酰谷胱甘肽水解酶缺乏症。其相关途径包括丙酮酸代谢和柠檬酸（TCA）循环与代谢。通过淀粉凝胶电泳程序，可以很容易地分离出人类和啮齿动物形式的乙醛酸酶 II（HAGH）。

生物活性

Measured by its ability to hydrolyze S-lactoylglutathione (L121369). The specific activity is >25,000 pmol/min/μg, as measured under the described conditions.

来源

重组表达

预测分子量

29.6 kDa

蛋白标签

C-His

SDS-PAGE

28.5 kDa, under reducing conditions; 28.8 kDa, under non-reducing conditions.

表达系统

E. coli Accession #: Q16775 | E. coli

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

1-260 aa

序列

MKVEVLPALTDNYMYLVIDDETKEAAIVDPVQPQKVVDAARKHGVKLTTVLTTHHHWDHAGGNEKLVKLESGLKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFTGDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCGHEYTINNLKFARHVEPGNAAIREKLAWAKEKYSIGEPTVPSTLAEEFTYNPFMRVREKTVQQHAGETDPVTTMRAVRREKDQFKMPRDHHHHHH

无动物源

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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