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Product details
名称
Recombinant Human Nicotinamide N-Methyltransferase/NNMT Protein
别名
重组人Nicotinamide N-Methyltransferase/NNMT蛋白
英文别名
EC 2.1.1.1 | Nicotinamide NMethyltransferase | Nicotinamide N-Methyltransferase | NNMT
货号
rp184926-10μg
包装规格
10μg
级别
无载体
浓度
≥95%(SDS-PAGE)
生化机理
NNMT(烟酰胺 N-甲基转移酶)是一种细胞膜酶,它以 S-腺苷-L-蛋氨酸(AdoMet)为甲基供体,催化烟酰胺和其他吡啶的 N-甲基化。这种酶在肝脏中的表达量很高,但在其他器官中也能检测到。NNMT 在烟酰胺代谢和异种生物解毒过程中发挥着重要作用。NNMT 与甲状腺癌和肾癌有关,因此可作为肿瘤生物标志物。催化烟酰胺和其他吡啶的 N-甲基化,形成吡啶鎓离子。这种活性对许多药物和异生物化合物的生物转化非常重要。 翻译后:被 PADI1 和 PADI2 清除。
来源
重组表达
预测分子量
30.3 kDa
蛋白标签
C-His
SDS-PAGE
27.0 kDa, under reducing conditions; 27.0 kDa, under non-reducing conditions.
表达系统
E. coli Accession #: P40261 | E. coli
内毒素水平
<1.0 EU/μg
种属
人(Human)
氨基酸
1-264 aa
序列
MESGFTSKDTYLSHFNPRDYLEKYYKFGSRHSAESQILKHLLKNLFKIFCLDGVKGDLLIDIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPEAFDWSPVVTYVCDLEGNRVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLDAACPDLPTYCRALRNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAVEAAVKEAGYTIEWFEVISQSYSSTMANNEGLFSLVARKLSRPLHHHHHH
无动物源
No
无载体
Yes
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
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「No related articles yet」
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Research chemical ≥95%

Research chemical ≥95%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥95%.

item number:rp184926-10μg
Product model:10μg
level: ≥95%
Lead Time:30days
sold 939 Items
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