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Product details
名称
Recombinant Human IL36 beta/IL-1F8 Protein
别名
重组人IL36 beta/IL-1F8蛋白 | 重组人IL36 beta蛋白 | 重组人 IL36 beta/IL-1F8 蛋白
英文别名
family of interleukin 1-eta | FIL1 eta | FIL1 | FIL1-(ETA) | FIL1H | FILI-(ETA) | IL-1 eta | IL1-ETA | IL1F8 (Canonical product IL-1F8a) | IL-1F8 (FIL1-eta) | IL1F8 | IL-1F8 | IL1H2 | Interleukin-36 Beta | Interleukin-1 Superfamily e | Interleukin-1 homol
货号
rp184957-10μg
包装规格
10μg
级别
无载体
浓度
≥95%(SDS-PAGE)
生化机理
白细胞介素-1 家族成员 8(IL1F8)又称 IL36B,是白细胞介素 1(IL-1)细胞因子家族的成员。IL1F8 可能含有 12 链 beta 三叶草结构。直到最近,IL-1 细胞因子家族还包括四个成员,其中三个具有促炎作用,如 IL1F8,第四个成员是 IL-1 受体拮抗剂(IL-1Ra)。IL-1 家族成员通过与属于 IL-1 受体(IL-1R)家族的受体结合来发挥其作用。IL1F8 在原发性人体关节细胞中发挥促炎作用。关节和血清中的IL-1F8蛋白水平与炎症并不相关,但在检测的一些人体血清样本中,包括类风湿性关节炎患者的样本中,IL-1F8蛋白水平很高。IL1F8 还能激活 NK-κB。 翻译后:N 端截短可显著增强其活性(>1000 倍)。
生物活性
Testing in progress
来源
重组表达
预测分子量
17.2 kDa
蛋白标签
No tag
SDS-PAGE
15.4 kDa, under reducing conditions; 15.4 kDa, under non-reducing conditions.
表达系统
E. coli Accession #: Q9NZH7 | E. coli
内毒素水平
<1.0 EU/μg
种属
人(Human)
氨基酸
5-157 aa
序列
REAAPKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGNMVYLGIKGKDLCLFCAEIQGKPTLQLKEKNIMDLYVEKKAQKPFLFFHNKEGSTSVFQSVSYPGWFIATSTTSGQPIFLTKERGITNNTNFYLDSVE​
无动物源
No
无载体
Yes
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
Articles
「No related articles yet」
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Research chemical ≥95%

Research chemical ≥95%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥95%.

item number:rp184957-10μg
Product model:10μg
level: ≥95%
Lead Time:30days
sold 797 Items
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