Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

Recombinant Human SULT1A1 Protein

别名

重组人SULT1A1蛋白

英文别名

货号

rp184967-10μg

包装规格

10μg

级别

无载体

浓度

≥95%(SDS-PAGE)

生化机理

硫酸盐结合由细胞膜磺基转移酶（SULT）催化。SULT 是第二阶段药物代谢酶，可催化内源性化合物（包括类固醇和神经递质）和某些外来生物（包括 N-hydroxy-2-acetylaminoflourine 和酚类化合物，如 alpha-萘酚）与硫酰基的结合。SULTs 可能与个体遗传倾向、物种差异和化学品毒理效应的有机体有关。特别是磺基转移酶 1 亚家族的成员 SULT1A1（磺基转移酶家族，胞浆，1A，酚优先，成员 1），它是人类药物代谢的主要途径。人类至少有 10 个功能性 SULT 基因。有关磺基转移酶多态性及其功能性后果的信息激增。SULT1A1 中的 Arg213His 多态性对血小板中的酶蛋白水平和活性有很大影响，而血小板已被广泛用于表型分析。据统计，SULT1A1 基因型（Arg213His）与年龄、肥胖和某些肿瘤（乳腺癌、肺癌、食管癌和尿道癌）之间存在明显关联。此外，SULT1A1 的多态性可能与乳腺癌密切相关。

生物活性

Testing in progress

来源

重组表达

预测分子量

34.9 kDa

蛋白标签

N-His

SDS-PAGE

30.9 kDa, under reducing conditions; 30.9 kDa, under non-reducing conditions.

表达系统

E. coli Accession #: P50225 | E. coli

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

2-295 aa

序列

MHHHHHHELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL

无动物源

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！