Recombinant Mouse CCL7/MARC Protein

重组小鼠CCL7蛋白 | 重组小鼠MARC蛋白 | 重组小鼠趋化因子配体7蛋白

C-C motif chemokine 7 | CCL7 | chemokine (C-C motif) ligand 7 | FIC | MARC | MCP-3 | MCP3Monocyte chemotactic protein 3 | MCP-3Small-inducible cytokine A7 | MGC138465 | Monocyte chemoattractant protein 3 | NC28SCYA6 | SCYA7MGC138463 | small inducible cyto

rp186590-10μg

10μg

无载体

≥90%(SDS-PAGE)

Mouse MARC, a member of the beta subfamily of chemokines, was initially identified as a transcript that is induced in a mouse mast cell line after Fc epsilon RI triggering by IgE plus antigen. Sequence comparisons suggest that MARC may be the mouse homologue of the human MCP-3 gene. Mouse MARC/MCP-3 expression has also been detected during murine experimental allergic encephalomyelitis in the spinal cord, and in LPS-stimulated murine WEHI -3 cells and Swiss 3T3 cells where MARC expression is glucocorticoid-attenuated. Except for one amino acid subsititution, mouse MARC is identical to mouse FIC, the product of a growth factor-activated gene. The mouse MARC cDNA encodes a 97 amino acid residue precursor protein with a 23 amino acid residue signal peptide that is cleaved to yield a 74 amino acid residue mature protein. Mouse CCR2, a mouse chemokine receptor, has been shown to bind JE/MCP-1 with high affinity and MARC/MCP-3 with lower affinity. The E. coli-expressed mouse MARC/MCP-3 produced at R&D Systems has been shown to be a monocyte and T-lymphocyte chemoattractant.

Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/mL.

重组表达

8.5 kDa

No tag

12.2 kDa, under reducing conditions; 12.9 kDa, under non-reducing conditions.

E. coli Accession #: Q03366 | E. coli

<1.0 EU/μg

小鼠(Mouse)

24-97 aa

QPDGPNASTCCYVKKQKIPKRNLKSYRRITSSRCPWEAVIFKTKKGMEVCAEAHQKWVEEAIAYLDMKTPTPKP

No

Yes