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Product details
名称
Recombinant Human CDK2AP2 Protein
别名
重组人CDK2AP2蛋白
英文别名
CDK2 associated protein 2 | CDK2-associated protein 2 | CDK2AP2 | CDKA2_HUMAN | Cyclin dependent kinase 2 associated protein 2 | Cyclin-dependent kinase 2-associated protein 2 | DOC 1 related protein | DOC-1-related protein | DOC-1R | DOC1R | FLJ10636 | p
货号
rp188225-10μg
包装规格
10μg
级别
无载体
浓度
≥95%(SDS-PAGE)
生化机理
CDK2AP2 属于 CDK2AP 家族。该蛋白家族的成员是细胞生长抑制因子,在 S 期与重要的细胞周期调节因子(包括单体非磷酸化的细胞周期蛋白依赖性激酶 2(CDK2)和 DNA 聚合酶 alpha/primase)结合并影响其生物活性。CDK2AP2 包含 5 个不同的 gt-ag 内含子。转录产生 7 种不同的 mRNA,其中 6 种是替代剪接变体,1 种是非剪接形式。有 2 个不重叠的替代性最后外显子和 4 个经过验证的替代性多腺苷酸化位点。这些 mRNA 的剪接与 3 个内含子的保留似乎有所不同。CDK2AP2 在许可条件下调节小鼠胚胎干细胞(mESC)的自我更新,以及在 mESC 分化为终末分化细胞类型的过程中调节细胞存活。 翻译后:被 MAPK1 和 CDK2 磷酸化。
来源
重组表达
预测分子量
13.9 kDa
蛋白标签
N-His
SDS-PAGE
14.2 & 33.1 kDa, under reducing conditions; 14.2 & 33.1 kDa, under non-reducing conditions.
表达系统
E. coli Accession #: O75956 | E. coli
内毒素水平
<1.0 EU/μg
种属
人(Human)
氨基酸
2-126 aa
序列
MHHHHHHSYKPIAPAPSSTPGSSTPGPGTPVPTGSVPSPSGSVPGAGAPFRPLFNDFGPPSMGYVQAMKPPGAQGSQSTYTDLLSVIEEMGKEIRPTYAGSKSAMERLKRGIIHARALVRECLAETERNART​
无动物源
No
无载体
Yes
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
Articles
「No related articles yet」
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Research chemical ≥95%

Research chemical ≥95%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥95%.

item number:rp188225-10μg
Product model:10μg
level: ≥95%
Lead Time:30days
sold 731 Items
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