Recombinant Human ECH1 Protein

重组人ECH1蛋白 | 重组人烯酰辅酶A水合酶1蛋白

4)-dienoyl-CoA isomerase | 5)-Delta(2 | Delta(3 | Delta(3 5) Delta(2 4) dienoyl CoA isomerase | Delta(3 5) Delta(2 4) dienoyl CoA isomerase mitochondrial | Delta3 5 delta2 4 dienoyl CoA isomerase | Dienoyl CoA isomerase | ECH 1 | Ech1 | ECH1_HUMAN | Enoyl

rp188244-10μg

10μg

无载体

≥95%(SDS-PAGE)

ECH1 is a member of the hydratase/isomerase superfamily. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. ECH1 contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. ECH1 functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

重组表达

33.2 kDa

N-His

30.1 kDa, under reducing conditions; 30.1 kDa, under non-reducing conditions.

E. coli Accession #: Q13011 | E. coli

<1.0 EU/μg

人(Human)

34-328 aa

MHHHHHHTGSSAQEEASGVALGEAPDHSYESLRVTSAQKHVLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGIDLMDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSRVFPDKEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLNYVASWNMSMLQTQDLVKSVQATTENKELKTVTFSKL

No

Yes