Recombinant Human CD3 zeta/CD247 Protein

重组人CD3 zeta/CD247蛋白 | 重组人T细胞表面糖蛋白CD3 ζ链

4930549J05Rik | A430104F18Rik | AW552088 | CD247 | CD247 antigen | Cd247 molecule | Cd3 | CD3 antigen, zeta polypeptide, isoform CRA_b | CD3 antigen, zeta subunit | CD3-eta | CD3H | CD3Q | Cd3z | CD3Z antigen zeta polypeptide (TiT3 complex) | CD3Z_HUMAN |

rp188342-10μg

10μg

无载体

≥90%(SDS-PAGE)

T-cell surface glycoprotein CD3 zeta chain (CD247) is a member of the CD3Z/FCER1G family. CD247 is T-cell receptor zeta, which along with T-cell receptor alpha/beta and gamma/delta heterodimers, and also with CD3-gamma, -delta and -epsilon, creates the T-cell receptor-CD3 complex. The zeta chain has a central role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the CD247 antigen causes impaired immune response. Post-translational: Phosphorylated on Tyr residues after T-cell receptor triggering by LCK in association with CD4/CD8.

Immobilized Recombinant Human CD3 zeta/CD247 Protein (rp188342) at 1.0 μg/mL can bind CD3 zeta Antibody (Ab094480) with the EC50 of 70.0 ng/mL.

重组表达

14.0 kDa

N-His

15.2 kDa, under reducing conditions; 15.2 kDa, under non-reducing conditions.

E. coli Accession #: P20963 | E. coli

<1.0 EU/μg

人(Human)

52-164 aa

MHHHHHHRVKFSRSADAPAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKPQRRKNPQEGLYNELQKDKMAEAYSEIGMKGERRRGKGHDGLYQGLSTATKDTYDALHMQALPPR

No

Yes