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Product details

名称

Recombinant Human p18 INK4c/CDKN2C Protein

别名

重组人p18 INK4c蛋白 | 重组人CDKN2C蛋白 | 重组人细胞周期抑制因子p18蛋白 | 重组人细胞周期依赖性激酶抑制因子2C蛋白

英文别名

货号

rp188348-10μg

包装规格

10μg

级别

无载体

浓度

≥95%(SDS-PAGE)

生化机理

Cyclin-Dependent Kinase 4 Inhibitor C (CDKN2C) is a member of the INK4 family of cyclin dependent kinase inhibitors. CDKN2C contains 4 ANK repeats and interacts with CDK4 or CDK6. Highest levels of CDKN2C can be found in skeletal muscle, pancreas, and heart. CDKN2C inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB and prevent the activation of the CDK kinases. Studies have been shown the roles of CDKN2C gene in regulating spermatogenesis, as well as in suppressing tumorigenesis.

生物活性

Immobilized Recombinant Human p18 INK4c/CDKN2C Protein (rp188348) at 2.0 μg/mL can bind Recombinant p18 INK4c/CDKN2C Antibody (Ab119609) with the EC50 of 6.68 ng/mL.

来源

重组表达

预测分子量

18.9 kDa

蛋白标签

N-His

SDS-PAGE

16.5 kDa, under reducing conditions; 16.5 kDa, under non-reducing conditions.

表达系统

E. coli Accession #: P42773 | E. coli

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

2-168 aa

序列

MHHHHHHAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ

无动物源

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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