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Product details
名称
Recombinant Human Cofilin 2 Protein
别名
重组人Cofilin 2蛋白
英文别名
CFL 2 | CFL2 | COF2_HUMAN | Cofilin | Cofilin 2 muscle | Cofilin muscle | Cofilin muscle isoform | Cofilin-2 | Cofilin2 | muscle isoform | NEM 7 | NEM7
货号
rp188353-10μg
包装规格
10μg
级别
无载体
浓度
≥95%(SDS-PAGE)
生化机理
Cofilin 2(肌肉)又称 CFL2,是肌动蛋白结合蛋白超家族中 cofilin 家族的成员。Cofilin2 在整个序列中与其他两个成员:Cofilin 1 和 DSTN 具有显著的同源性,并含有在 Cofilin 家族中保守的负责肌动蛋白结合的残基。Cofilin 2(CFL2)是横纹肌细胞功能的重要调节因子。纯化的Cofilin 2以剂量和pH依赖性的方式解聚肌动蛋白丝,并降低肌动蛋白溶液的表观粘度,尽管它们根本不与肌动蛋白丝共同沉积。Cofilin2 在无性细胞中不表达,但在发育的聚集阶段会被短暂诱导,而 cofilin 1 则主要在无性细胞中表达。 翻译后:Ser-24 的磷酸化可能会阻止核定位信号的识别。
来源
重组表达
预测分子量
19.6 kDa
蛋白标签
N-His
SDS-PAGE
19.7 kDa, under reducing conditions; 19.7 kDa, under non-reducing conditions.
表达系统
E. coli Accession #: Q9Y281 | E. coli
内毒素水平
<1.0 EU/μg
种属
人(Human)
氨基酸
2-166 aa
序列
MHHHHHHASGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDIGDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL​
无动物源
No
无载体
Yes
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
Articles
「No related articles yet」
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Research chemical ≥95%

Research chemical ≥95%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥95%.

item number:rp188353-10μg
Product model:10μg
level: ≥95%
Lead Time:30days
sold 176 Items
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