Recombinant Human CUTC Protein

重组人CUTC蛋白 | 重组人CutC铜转运蛋白

CGI 32 | CGI32 | Copper homeostasis protein cutC homolog | cutC | CutC copper transporter homolog (E. coli) | CUTC_HUMAN | RP11-483F11.3

rp188364-10μg

10μg

无载体

≥95%(SDS-PAGE)

Copper homeostasis protein cutC homolog, also known as CGI-32 and CUTC, is a cytoplasm and nucleus protein which belongs to theCutC family. CUTC may play a role in copper homeostasis. It can bind one Cu1+per subunit. Copper is an essential trace element to life and particularly plays a pivotal role in the physiology of aerobic organisms. Copper is a micronutrient that is required for proper metabolic functioning of most prokaryotic and eukaryotic organisms. To sustain an adequate supply of copper, a cell requires molecular mechanisms that control the metal content to avoid copper toxicity. This toxicity comes primarily from the reactivity of copper, which can lead to the generation of free radicals. In bacteria, two independent systems are responsible for maintaining the balance of copper within the cells ( Cop and Cut family proteins ). The Cut protein family is associated with copper homeostasis and involved in uptake, storage, delivery, and efflux of copper. CutC is a member of the Cut family and is suggested to be involved in efflux trafficking of cuprous ion. CutC is able to respond transcriptionally to copper and to participate in the control of copper homeostasis in E. faecalis. May play a role in copper homeostasis. Can bind one Cu1+ per subunit.

重组表达

30.2 kDa

N-His

29.4 & 58.6 kDa, under reducing conditions; 28.9 & 55.5 kDa, under non-reducing conditions.

E. coli Accession #: Q9NTM9 | E. coli

<1.0 EU/μg

人(Human)

2-273 aa

MHHHHHHKRQGASSERKRARIPSGKAGAANGFLMEVCVDSVESAVNAERGGADRIELCSGLSEGGTTPSMGVLQVVKQSVQIPVFVMIRPRGGDFLYSDREIEVMKADIRLAKLYGADGLVFGALTEDGHIDKELCMSLMAICRPLPVTFHRAFDMVHDPMAALETLLTLGFERVLTSGCDSSALEGLPLIKRLIEQAKGRIVVMPGGGITDRNLQRILEGSGATEFHCSARSTRDSGMKFRNSSVAMGASLSCSEYSLKVTDVTKVRTLNAIAKNILV

No

Yes