Recombinant Human RCAS1/EBAG9 Protein

重组人RCAS1/EBAG9蛋白 | 重组人雌激素受体结合位点相关抗原 9 | 重组人SiSo细胞上表达的受体结合癌抗原

BAG9 | Cancer associated surface antigen | Cancer associated surface antigen RCAS1 | Cancer-associated surface antigen RCAS1 | EB9 | EBAG 9 | EBAG9 | Estrogen receptor binding fragment associated gene 9 protein | Estrogen receptor binding site associated

rp188379-10μg

10μg

无载体

≥90%(SDS-PAGE)

RCAS1, also known as EBAG9, is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. RCAS1 gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of RCAS1 gene. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for RCAS1 gene. EBAG9 may participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

Immobilized Recombinant Human RCAS1 Protein (rp188379) at 1.0 μg/mL can bind RCAS1 Mouse mAb (Ab124859) with the EC50 of 33.9 ng/mL.

重组表达

22.2 kDa

N-His

30.7 kDa, under reducing conditions; 30.7 kDa, under non-reducing conditions

E. coli Accession #: O00559 | E. coli

<1.0 EU/μg

人(Human)

28-213 aa

MHHHHHHRSGRGRKLSGDQITLPTTVDYSSVPKQTDVEEWTSWDEDAPTSVKIEGGNGNVATQQNSLEQLEPDYFKDMTPTIRKTQKIVIKKREPLNFGIPDGSTGFSSRLAATQDLPFIHQSSELGDLDTWQENTNAWEEEEDAAWQAEEVLRQQKLADREKRAAEQQRKKMEKEAQRLMKKEQNKIGVKLS

No

Yes