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Product details

名称

Recombinant Human Glutathione Synthetase Protein

别名

重组人Glutathione Synthetase蛋白 | 重组人谷胱甘肽合成酶蛋白

英文别名

Glutathione Synthetase | GSH Synthetase | GSH-S | Glutathione Synthase | GSS

货号

rp188403-10μg

包装规格

10μg

级别

无载体

浓度

≥95%(SDS-PAGE)

生化机理

Catalyzes the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner (PubMed:7646467, PubMed:9215686). Glutathione (gamma-glutamylcysteinylglycine, GSH) is the most abundant intracellular thiol in living aerobic cells and is required for numerous processes including the protection of cells against oxidative damage, amino acid transport, the detoxification of foreign compounds, the maintenance of protein sulfhydryl groups in a reduced state and acts as a cofactor for a number of enzymes (PubMed:10369661). Participates in ophthalmate biosynthesis in hepatocytes (By similarity).

生物活性

Immobilized Recombinant Human Glutathione Synthetase Protein (rp188403) at 1.0 μg/mL can bind Recombinant Glutathione Synthetase Antibody (Ab105758) with the EC50 of 7.1 ng/mL.

来源

重组表达

预测分子量

53.2 kDa

蛋白标签

C-His

SDS-PAGE

49.6 kDa, under reducing conditions; 49.6 & 49.8 kDa, under non-reducing conditions.

表达系统

E. coli Accession #: P48637 | E. coli

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

1-474 aa

序列

MATNWGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQAYAVQMDFNLLVDAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQRSADGSPALKQIEINTISASFGGLASRTPAVHRHVLSVLSKTKEAGKILSNNPSKGLALGIAKAWELYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFEDISEKGSLDQDRRLFVDGQEIAVVYFRDGYMPRQYSLQNWEARLLLERSHAAKCPDIATQLAGTKKVQQELSRPGMLEMLLPGQPEAVARLRATFAGLYSLDVGEEGDQAIAEALAAPSRFVLKPQREGGGNNLYGEEMVQALKQLKDSEERASYILMEKIEPEPFENCLLRPGSPARVVQCISELGIFGVYVRQEKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPVHHHHHH

无动物源

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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