Recombinant Human PSMA3 Protein

重组人PSMA3蛋白 | 重组人蛋白酶体20S亚基alpha 3蛋白

HC8 | Macropain subunit C8 | MGC12306 | MGC32631 | Multicatalytic endopeptidase complex subunit C8 | Proteasome (prosome macropain) subunit alpha type 3 | Proteasome alpha 3 subunit | Proteasome component C8 | Proteasome subunit alpha type 3 | Proteasome

rp188417-10μg

10μg

无载体

≥95%(SDS-PAGE)

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2.

Immobilized Recombinant Human PSMA3 Protein (rp188417) at 1.0 μg/mL can bind Recombinant PSMA3 Antibody (Ab123648) with the EC50 of 29.2 ng/mL.

重组表达

29.3 kDa

N-His

27.8 kDa, under reducing conditions; 27.8 kDa, under non-reducing conditions.

E. coli Accession #: P25788 | E. coli

<1.0 EU/μg

人(Human)

2-255 aa

MHHHHHHSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKEEDESDDDNM

No

Yes