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Product details
名称
Recombinant Human S100A3 Protein
别名
重组人S100A3蛋白
英文别名
Protein S 100E | Protein S-100E | Protein S100 A3 | Protein S100-A3 | S100 calcium binding protein A3 | S100 calcium-binding protein A3 | S100a3 | S100E | S10A3_HUMAN
货号
rp188430-10μg
包装规格
10μg
级别
无载体
浓度
≥95%(SDS-PAGE)
生化机理
蛋白质 S100-A3,又称蛋白质 S-100E、S100 钙结合蛋白 A3、S100A3 和 S100E,是 S-100 家族的成员。S100A3 / S100E 含有 2 个 EF-手结构域。S100A3 / S100E 在毛囊内分化的角质细胞中高度表达,并组织成成熟的毛发角质层。高浓度的 S100A3 同源四聚体可提供毛发角质层屏障形成所需的毫摩尔级 Ca2+。S100A3 / S100E 是 Ca2+ 结合型 S100 蛋白家族中的独特成员,其半胱氨酸含量最高,对 Zn2+ 的亲和力也最强。S100A3 / S100E 同时与钙和锌结合。S100A3 / S100E 每个分子可能结合 2 个锌离子。它可能参与钙依赖性角质层细胞分化和毛干的形成。S100A3 在毛干形成的钙依赖过程中发挥重要作用。S100A3 / S100E 是钙结合 S100 家族所有成员中的一种独特蛋白质,特异性地表达于人类毛发纤维的内侧内囊。毛发受损时,S100A3 / S100E 会从毛发纤维中释放出来,并可能破坏毛发组织结构的稳定性。 翻译后:一半以上的精氨酸残基会被 PAD1 和 PAD2 瓜氨酸化。Arg-51 被 PAD3 特异性瓜氨酸化,并促进四聚体化。
来源
重组表达
预测分子量
12.5 kDa
蛋白标签
N-His
SDS-PAGE
11.8 kDa, under reducing conditions; 11.8 kDa, under non-reducing conditions.
表达系统
E. coli Accession #: P33764 | E. coli
内毒素水平
<1.0 EU/μg
种属
人(Human)
氨基酸
2-101 aa
序列
MHHHHHHARPLEQAVAAIVCTFQEYAGRCGDKYKLCQAELKELLQKELATWTPTEFRECDYNKFMSVLDTNKDCEVDFVEYVRSLACLCLYCHEYFKDCPSEPPCSQ
无动物源
No
无载体
Yes
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
Articles
「No related articles yet」
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Research chemical ≥95%

Research chemical ≥95%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥95%.

item number:rp188430-10μg
Product model:10μg
level: ≥95%
Lead Time:30days
sold 176 Items
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10μg

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