Recombinant Human CFLAR Protein

重组人CFLAR蛋白 | 重组人CASP8和FADD样细胞凋亡调节因子蛋白

c FLIP | c FLIPL | c FLIPR | c FLIPS | c-FLIP | c-FLIPL | c-FLIPR | Usurpin beta | Usurpin | OTTHUMP00000207360 | OTTHUMP00000206482 | OTTHUMP00000206480 | OTTHUMP00000206479 | OTTHUMP00000206478 | OTTHUMP00000206476 | OTTHUMP00000206475 | c-FLIPS | CASH

rp189315-10μg

10μg

无动物源

≥90%(SDS-PAGE)

Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity. Post-translational: Proteolytically processed by CASP8 generating subunit p43 and p12.

重组表达

32.7 kDa

N-His

29.2 kDa, under reducing conditions; 29.2 & 60.7 kDa, under non-reducing conditions.

E. coli Accession #: O15519 | E. coli

<1.0 EU/μg

人(Human)

2-277 aa

MHHHHHHSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLYRVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTSYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIPEERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYE​

No

Yes