Recombinant Human Proteasome subunit beta type 2/PSMB2 Protein

重组人Proteasome subunit beta type 2/PSMB2蛋白 | 重组人蛋白酶体20S亚基β 2蛋白

HC7 I | Macropain subunit C7 I | Macropain subunit C7-I | Multicatalytic endopeptidase complex subunit C7 1 | Multicatalytic endopeptidase complex subunit C7 I | Multicatalytic endopeptidase complex subunit C7-I | Proteasome (prosome, macropain) subunit b

rp189463-10μg

10μg

无载体

≥90%(SDS-PAGE)

Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).

重组表达

23.7 kDa

N-His

21.5 kDa, under reducing conditions; 20.7 & 38.3 & 40.3 kDa, under non-reducing conditions.

E. coli Accession #: P49721 | E. coli

<1.0 EU/μg

人(Human)

2-201 aa

MHHHHHHEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSVRIIDKNGIHDLDNISFPKQGS

No

Yes