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Product details

名称

Recombinant Human EIF3S1/EIF3J Protein

别名

重组人EIF3S1/EIF3J蛋白 | 重组人真核翻译起始因子3亚基J蛋白

英文别名

货号

rp192076-10μg

包装规格

10μg

级别

无载体

浓度

≥90%(SDS-PAGE)

生化机理

Eukaryotic translation initiation factor 3 subunit J (EIF3J) is a member of the EIF-3 subunit J family. EIF3 has a crucial role in binding of initiator methionyl-tRNA and mRNA to the 40S ribosomal subunit to produce the 40S initiation complex. EIF3J binds to the aminoacyl (A) site and mRNA access channel of the 40S subunit, setting EIF3J directly in the ribosomal decoding center. In addition, EIF3J interacts with eIF1A and reduces 40S subunit affinity for mRNA. An elevated affinity for mRNA is restored upon enlistment of initiator tRNA, despite the fact EIF3J remains in the mRNA-binding cleft in the presence of tRNA. Post-translational: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

生物活性

Immobilized Recombinant Human EIF3S1/EIF3J Protein (rp192076) at 1.0 μg/mL can bind EIF3S1/EIF3J Antibody (Ab101341) with the EC50 of 72.7 ng/mL.

来源

重组表达

预测分子量

22.7 kDa

蛋白标签

N-His

SDS-PAGE

26.6 kDa, under reducing conditions; 26.6 kDa, under non-reducing conditions.

表达系统

E. coli Accession #: O75822 | E. coli

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

70-258 aa

序列

MHHHHHHKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSLYYASFLEVLVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDLADYGGYDGGYVQDYEDFM

无动物源

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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