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名称
细胞色素C 来源于牛心
英文别名
CYCHCS | CYCS | Cytochrome c | cytochrome c, somatic | THC4 | cytc
货号
rp222683-100mg
包装规格
100mg
级别
BioReagent
浓度
≥95%(SDS-PAGE)
产品介绍
细胞色素c的主要身份是电子载体线粒体蛋白。在细胞内,细胞色素c能够在二价铁和三价铁之间转化,使得它称为了有效的生物电子载体,在动植物细胞内氧化中起到很重要的作用。它通常被视作呼吸作用催化剂,在呼吸底物和氧气之间形成必需的电子桥。 处理说明 使用TCA制备。 当在10毫克/毫升的水中溶解时,本产品在溶液中应为深红色至红棕色。 在2-8°C下短期储存时,溶液可保持活性。溶液分装后可在-20°C冷冻并保持稳定。 产品应用 细胞色素C已用于: 1、还原由黄嘌呤氧化酶生成的超氧自由基-铁氧化铬c 2、采用MALDI质谱法,用单液滴沉积法进行分析 3、作为标准细胞色素c还原酶活性测定的末端电子受体 4、细胞色素c氧化酶组织化学 5、用于细胞色素C氧化酶活性的测定 6、作为磷酸盐缓冲液的组分,用于采用蓝色天然凝胶电泳(BN-PAGE)检测和评估复合物IV活性 7、用于检测离体肾脏吞噬细胞中的细胞外超氧阴离子(ECSA)
生化机理
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity).
来源
天然
种属
牛(Bovine)
Safety
「No Dangerous Attributes」
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Research chemical 100mg; ≥95%

Research chemical 100mg; ≥95%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 100mg; ≥95%.

item number:rp222683-100mg
Product model:100mg
level: 100mg; ≥95%
Lead Time:30days
sold 500 Items
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100mg

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