What does separation and purification mean? separation
Separation and purification is the separation of traditional Chinese medicine extract from residue, sediment and solid impurities, and then the use of advanced and reasonable separation and purification technology to remove ineffective components and retain active and auxiliary components. Commonly used separation methods include filtration separation, sedimentation separation and centrifugal separation.
Due to the complex ingredients of traditional Chinese medicine, the content can be high or low, the selection of separation and purification methods should be based on the physical and chemical properties of the ingredients contained in the medicinal materials, the selected dosage form of the preparation and the molding process, and the necessary process verification is required to determine. According to the active ingredients in traditional Chinese medicine dissolved in water or dissolved inEthanolThe most commonly used methods for the extraction and separation of traditional Chinese medicine are water extraction and alcohol precipitation method and alcohol extraction and water precipitation method. According to the properties of the active ingredients contained in the medicinal materials and the characteristics of the selected dosage form and molding process, flocculation precipitation method, membrane separation method, dialysis method, salting out method, ion exchange method, macroporous resin adsorption method, polyamide adsorption method, silica gel adsorption chromatography method, molecular distillation method, enzymatic hydrolysis method and other separation methods can also be used to separate and purify the extract of traditional Chinese medicine
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