Fibronectin in cell culture
As a biochemical reagent, fibronectin provides the basis for the industrial application of cell culture and bioengineering. Let me tell you about it belowIt's incellWhat role did the cultivation process play?
In fact, among the many functions of fibronectin, the most basic and important one is to promote cell adhesion and growth, and cell adhesion is a necessary condition for the maintenance of body structure and the completion of cell growth. Therefore, fibronectin is one of the important components of cell culture medium. Biologists have used porcine plasma fibronectin research results show that: fibronectin as the substrate of cell culture can make a variety of cells adhere to the wall rate of more than 90% (control group is 10%), cell morphology and structure are good, cell metabolic rate is enhanced, DNA, RNA and protein synthesis rate increased by about 5 times, cell colony rate increased several times, the survival rate of primary culture is significantly improved, cell growth time is shortened, which is very beneficial for the establishment of human disease in vitro model. Studies have also proved that fibronectin can improve the fusion rate of cells, shorten the fusion cycle, can be applied to many scientific research, such as cell hybridoma technology. Coating FN onto the microsphere carrier as a medium for mass production of cells can save space and raw materials, and become the basic substance for the application of cell culture technology to produce new drugs. Cell culture technology is one of the methods often used in biological research today, and it is also one of the indispensable means of bioengineering.
Therefore, the development of fibronectin products will play a positive role in promoting the wide application of cell culture and the application and development of bioengineering. The use of fibronectin as a biochemical reagent will increase day by day, and the market potential is great.
