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Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Target: NRTIs; HBV Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Adefovir Dipivoxil is used for treatment of hepatitis B and herpes simplex virus infection [1-3]. Adefovir Dipivoxil is approved for the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (primarily ALT) or histologically active disease. Adefovir Dipivoxil is a failed treatment for HIV[3, 4]. Adefovir dipivoxil 是一种腺苷类似物，是核苷逆转录酶 (nucleoside reverse transcriptase) 抑制剂 Adefovir 的口服前体。Adefovir dipivoxil 对 Lamivudine 耐药株和野生型菌株均有抑制作用。Adefovir dipivoxil 具有抗正痘病毒活性。 Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Target: NRTIs; HBV Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Adefovir Dipivoxil is used for treatment of hepatitis B and herpes simplex virus infection [1-3]. Adefovir Dipivoxil is approved for the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (primarily ALT) or histologically active disease. Adefovir Dipivoxil is a failed treatment for HIV[3, 4]. Catalyst employed in the Sharpless Asymmetric Dihyroxylation of ( E , E )- or ( E , Z )-1,3-dienoates. 1 Also used in the preparation of ?-hydroxy-γ-lactones from ?,γ-unsaturated esters. 2 Product Introduction: Adefovir dipivoxil, an adenosine analogue, is an oral proagent of the nucleoside reverse transcriptase inhibitor Adefovir. Adefovir dipivoxil inhibits both the wild type and HBV Lamivudine-resistant strains. Adefovir dipivoxil shows anti-orthopoxvirus activity.

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Chinese name

阿德福韦酯

English name

Adefovir Dipivoxil

Chinese alias

阿德伏韦酯 | 阿德幅韦二脂 | 9-[2-[双(新戊酰氧基甲氧基)磷酰甲氧基]乙基]腺嘌呤

English alias

9-[2-[Bis(pivaloyloxymethoxy)phosphorylmethoxy]ethyl]adenine | 9-(2[bis(Pivaloyloxymethoxy)phosphorylmethoxy]ethyl)adenine

CAS number

142340-99-6

molecular formula

C20H32N5O8P

molecular weight

501.47 g/mol

Exact mass

≥99%

PSA

167.000 Å²

Logp

1.8

Technical Documents

14 2340-99 - 6 | Adefovir dipivoxil | Adefovir dipivoxil
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