Share to
Overview
Specs
Safety
Technical Documents
Related
Articles
reviews
Consult
returns
Product introduction
米托蒽醌是一种二羟基蒽醌,是在5和8位被6-羟基-1,4-二氮杂己基取代的1,4-二羟基-9,10-蒽醌。它具有镇痛和抗肿瘤药物的作用。
Chinese name
米托蒽醌, DNA 拓扑异构酶 IIα 抑制剂
English name
1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione
Chinese alias
1,4-二羟基-5,8-双[[2-[(2-羟乙基)氨基]乙基]氨基]蒽醌 | 1,4-二羟基-5,8-双[[2-[(2-羟乙基)氨基]乙基]氨基]蒽-9,10-二酮
English alias
L01DB07 | 5,8-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)-1,4-dihydroxyanthraquinone | HMS2090D05 | 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione | DTXSID4046947 | Mitoxanthrone | 1,4-DIHYDROXY-5,8-BIS((2-((2-HYDROXYETHY
CAS number
65271-80-9
molecular formula
C22H28N4O6
molecular weight
444.5
Exact mass
-
PSA
163
Logp
1
Safety
  • exposure pathway: 静脉注射。口服后吸收不良。
  • Toxicity summary: 米托蒽醌是一种通过氢键与脱氧核糖核酸(DNA)相互作用的DNA反应性试剂,可引起交联和链断裂。米托蒽醌还干扰核糖核酸(RNA),并是拓扑异构酶II的有效抑制剂,该酶负责解开和修复受损DNA。它对增殖和非增殖培养的人体细胞都具有细胞毒性,表明缺乏细胞周期特异性。
  • Regulatory information: 加州化妆品安全计划(CSCP)报告成分:报告 - 无论成分在产品中的预期功能如何
  • Health Effects: 心肌病是一个特别值得关注的影响,因为它不可逆。[维基百科]
  • Hepatotoxicity: 可能性评分: D(可能是临床上明显的肝损伤的罕见原因)。
  • Symptoms and Signs: 严重白细胞减少伴感染。
  • Hazard categories and classifications: 水环境慢性2(100%)
  • Carcinogen Classification: 2B,可能对人类致癌。(L135)
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: 截至修订日期,未找到相关已发表信息。
Technical Documents
「No technical documents」
Related
「No upstream and downstream information yet」
Articles
「No related articles yet」
user reviews
Loading...
Consultation

Warm reminder:

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.!

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ,We will handle it for you as soon as possible, thank you for your support and trust.!

Research chemical ≥97. 0%; 100mg

Research chemical ≥97. 0%; 100mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥97. 0%; 100mg.

item number:717248-100mg
Product model:100mg
level: ≥97. 0%; 100mg
Lead Time:-
sold 219 Items
Ask Solution engineer
Qty

Recommended for you