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Product introduction

圆弧偶氮酸（CPA）是由多种曲霉和青霉菌种合成的tetramic酸。应用圆弧青霉菌来源圆弧偶氮酸用于：作为标准品，用于薄层色谱法（TLC）检测和定量黄曲霉毒素。作为培养基成分，用于不含Ca2+的DMEM（含10％胎牛血清（FBS））。作为肌质网/内质网Ca2+ -ATP酶的可逆抑制剂，检测腔内钙在内质网（ER）-至-高尔基体转运过程中的作用。作为内质网Ca2+-ATP酶的阻滞剂，处理神经元；研究内质网（ER）在Ca2+诱导的Ca2+ 释放（CICR）抑制 SERCA 过程中，对释放和维持Ca2+ 的影响。 Cyclopiazonic acid (CPA), a tetramic acid is synthesized by various Aspergillus and Penicillium species. Product Application Cyclopiazonic acid from Penicillium cyclopium has been used: as a standard in aflatoxin detection and quantification by thin layer chromatography (TLC) as a component in Ca2+-free DMEM/10% fetal bovine serum (FBS) as a reversible inhibitor of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) to examine the role of luminal calcium in endoplasmic recticulum (ER)-to-Golgi trafficking as an endoplasmic reticulum Ca2+-ATPase blocker, to treat neurons and also to study the role of the endoplasmic reticulum (ER) in releasing and sustaining Ca2+ during Ca2+-induced Ca2+ release (CICR) to inhibit SERCA

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Chinese name

环盐酸吗甲吡嗪酸来源于圆弧青霉菌

English name

Cyclopiazonic acid from Penicillium grisefulvum

Chinese alias

环匹阿尼酸,环二氮酸

English alias

NSC 117181，(6aS,11aR,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-6a,7,11a,11b-tetrahydro-2H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9(6H)-one，

CAS number

18172-33-3

molecular formula

C20H20N2O3

molecular weight

336.38 g/mol

Exact mass

≥98%

PSA

Logp

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