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Product introduction

VX-661是一种vertex衍生物，可校正F508del-CFTR转运，并可在体外增加F508del-CFTR蛋白的活性。 VX-661 is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.

Specs ⸢ View details ⸥

Chinese name

VX-661, 囊性纤维化跨膜传导调节器正调节器

English name

VX-661

Chinese alias

1-(2,2-二氟-1,3-苯并二氧戊环-5-基)-N-[1-[(2R)-2,3-二羟基丙基]-6-氟-2-(2-羟基-1,1-二甲基乙基)-1H-吲哚-5-基]-环丙烷甲酰胺

English alias

1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide | EN300-7398484 | TRIKAFTA COMPONENT TEZACAFTOR | 1-(2,2-difluoro-1,3-dioxaindan-5-yl)-N-{1-[(2R)-2,3-dih

CAS number

1152311-62-0

molecular formula

C26H27F3N2O6

molecular weight

520.5 g/mol

Exact mass

PSA

113.000 Å²

Logp

2.9

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