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Product introduction
物理描述 | 青霉素V是白色结晶粉末。(NTP, 1992)
Chinese name
青霉素V
English name
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Chinese alias
-
English alias
(2s-(2alpha,5alpha,6beta))-enoxyacetyl)amino); 3,3-dimethyl-7-oxo-6-[(phenyloxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptan; 6-phenoxyacetamido-penicillanicaci; 6-phenoxyacetamidopenicillanicacid; acipenv; apopen; calcipen; compocillinv
CAS number
87-08-1
molecular formula
C16H18N2O5S
molecular weight
350.4
Exact mass
-
PSA
121
Logp
2.1
Safety
  • Health hazard: 症状:接触此化合物的症状包括超敏反应、皮疹、接触性皮炎、口腔病变、发热、嗜酸性粒细胞增多、间质性肾炎、血管性水肿、血清病、过敏反应、"Arthus"现象;胃肠道刺激;静脉炎;支气管收缩伴有严重哮喘,或腹痛、恶心、呕吐、极度虚弱和血压下降、腹泻,以及紫癜性皮肤爆发。(NTP, 1992)
  • Storage conditions: 商业青霉素V...片剂和口服混悬液或溶液的粉末应储存在15-30°C的密闭容器中。
  • reactive group: 硫化物,有机
  • Disposal method: SRP:在审查时,土地处理或填埋(卫生填埋)处置实践的标准正在重大修订中。在实施废物残渣(包括废物污泥)的土地处置之前,咨询环境监管机构以获取可接受的处置实践指导。
  • First aid measures: 食入:不要催吐。如果受害者意识清醒且没有抽搐,给予1-2杯水稀释化学物质,并立即呼叫医院或中毒控制中心。如果医生建议,准备将受害者送往医院。如果受害者抽搐或昏迷,不要经口给予任何东西,确保受害者的气道通畅,让受害者侧卧,头部低于身体。不要催吐。立即将受害者送往医院。(NTP, 1992)
  • fire hazard: 该化学品的闪点数据不可用;但它可能是可燃的。(NTP, 1992)
  • fire fighting: 涉及此材料的火灾可以用干化学灭火器、二氧化碳或哈龙灭火器控制。(NTP, 1992)
  • reactivity profile: 在空气中稳定至37%;对酸相对稳定。该化合物与酸、氧化剂(特别是在存在痕量金属时)、铜、铅、锌和汞等重金属离子;甘油、拟交感胺、硫柳汞、木醇、鲸蜡醇、硬石蜡、聚乙二醇、可可脂和许多离子和非离子表面活性剂不相容。它也与碱、硫化橡胶中浸出的化合物、四环素的盐酸盐和有机过氧化物不相容。其他不相容物质包括还原剂、醇类、其他羟基化合物、自乳化鲸蜡醇、乳化蜡、羊毛脂、粗胆碱酯碱、乙二醇、糖类、胺类、阿米氯盐酸盐、麻黄碱、普鲁卡因、橡胶管、盐酸硫胺素...
  • Other safety information: 化学品评估:IMAP评估 - 4-硫杂-1-氮杂双环[3.2.0]庚烷-2-甲酸,3,3-二甲基-7-氧代-6-[(苯氧乙酰基)氨基]-,[2S-(2α,5α,6β)]-:环境I级评估
  • Air and water reaction: 不溶于水。
  • Hazard categories and classifications: 呼吸道致敏物1级(100%)
  • Non-fire leakage response: 储存注意事项:您应在冷冻条件下储存此物质。(NTP, 1992)
  • Personal protective equipment (PPE): 推荐呼吸器:在称量和稀释纯测试化学品时,佩戴NIOSH批准的半面罩呼吸器,配备有机蒸气/酸性气体 cartridges(专门用于有机蒸气、HCl、酸性气体和SO2)和粉尘/雾过滤器。(NTP,1992)
  • Possible routes of human exposure: 兽医、医生、护士和药剂师在处理青霉素制剂后偶尔会接触性皮炎。
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: 截至修订日期,未找到相关已发表信息。
Technical Documents
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Related
upstream information
Manufacturing method:
青霉素(CID:2349);苯氧乙酸(CID:19188);2-苯氧乙醇(CID:17972278)
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Research chemical 95. 2%; 10mg

Research chemical 95. 2%; 10mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 95. 2%; 10mg.

item number:75397-10mg
Product model:10mg
level: 95. 2%; 10mg
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sold 80 Items
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