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Product introduction

AT7867是ATP竞争性Akt1/2/3和p70S6K/PKA抑制剂，IC50分别为32 nM/17 nM/47 nM和85 nM/20 nM，对AGC激酶家族以外的蛋白几乎无活性。A potent ATP-competitive inhibitor of Akt1, Akt2 and Akt3 AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family. A potent ATP-competitive inhibitor of Akt1, Akt2 and Akt3

Specs ⸢ View details ⸥

Chinese name

4-(4-氯苯基)-4-[4-(1H-吡唑-4-基)苯基]哌啶(AT7867)

English name

AT7867

Chinese alias

4-(4-氯苯基)-4-[4-(1H-吡唑-4-基)苯基]哌啶

English alias

4-(4-(1H-pyrazol-4-yl)phenyl)-4-(4-chlorophenyl)piperidine | BDBM16219 | CHEBI:82708 | FT-0746989 | PS-3255 | SCHEMBL1977655 | EX-8670 | HMS3655A05 | NSC 61876 | SW219380-1 | J-513483 | A24956 | DTXSID00457772 | BP-12616 | NCGC00346549-06 | DB07859 | Q270

CAS number

857531-00-1

molecular formula

C20H20ClN3

molecular weight

337.86 g/mol

Exact mass

≥98%

PSA

40.700 Å²

Logp

4.300

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