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Product introduction
Aripiprazole是一种人5-HT1A受体激动剂,Ki为4.2 nM。 阿立哌唑的主要成分为 3, 4 二氢-2-(1H) 喹啉酮。 阿立哌唑已被用于研究其对乳腺肿瘤发生的影响,通过逆转录病毒传递受体酪氨酸蛋白激酶 2 或 HRas 原癌基因、gtp 酶或通过转基因表达 Wnt-1(原癌蛋白)介导。也用于研究其对幼年自发性高血压大鼠的行为和神经化学作用。 阿立哌唑已被用于研究阿立哌唑对注意缺陷多动障碍 (ADHD) 模型幼年自发性高血压大鼠 (SHR) 的行为和神经化学的影响。 A selective dopamine D2-receptor antagonist showing autoreceptor agonist activity. Aripiprazole is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM A selective dopamine D2-receptor antagonist showing autoreceptor agonist activity. Aripiprazole has been used to study behavioral and neurochemical effects of aripiprazole treatment in juvenile spontaneously hypertensive rats (SHR), a model for attention deficit hyperactivity disorder (ADHD). Aripiprazole has been used to study its effect on mammary tumorigenesis, mediated by retrovirus delivery of receptor tyrosine-protein kinase 2 or HRas proto-oncogene, GTPase or by transgenic expression of Wnt-1 (proto-oncoprotein). It has also been used to study its behavioral and neurochemical effects in juvenile spontaneously hypertensive rats.
Chinese name
阿立哌唑, 羟色胺 2a(5-HT2a)受体拮抗剂
English name
Aripiprazole
Chinese alias
阿立哌唑 | 7-[4-[4-(2, 3-二氯苯基)-1-哌嗪基]丁氧基]-3, 4-二氢-2(1H)-喹啉酮 | 7-[4-[4-(2,3-二氯苯基)-1-哌嗪基] 丁氧基]-3,4-二氢-2 (1H)-喹啉酮 | 7-{4-[4-(2,3-二氯苯基)-L-哌嗪基]丁氧基}-3,4-二氢-2(1H)-喹啉酮
English alias
7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydrocarbostyril | Aripiprazole [USAN:INN:BAN] | Aripiprazole- Bio-X | HMS3373D04 | Asprito | BCP04902 | OPC-14597 | s1975 | Aripiprex | Pripiprazole | Abilify Maintena Kit | Abilify MyCite
CAS number
129722-12-9
molecular formula
C23H27Cl2N3O2
molecular weight
448.39 g/mol
Exact mass
-
PSA
44.800 Ų
Logp
4.6
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Research chemical

Research chemical; supplied for laboratory research, analysis, inspection, and scientific procurement use.

item number:A408016-1ml
Product model:1ml
level:
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