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Product introduction

Apixaban是一种高度选择性，可逆的凝血因子 Xa 抑制剂，抑制人和兔凝血因子 Xa 的 Ki 值分别为 0.08 nM 和 0.17 nM。Apixaban 正在开发用于预防和治疗各种血栓栓塞疾病。 Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively. Apixaban is in development for the prevention and treatment of various thromboembolic diseases.

Specs ⸢ View details ⸥

Chinese name

阿哌沙班, 凝血因子 X 抑制剂

English name

Apixaban

Chinese alias

阿哌沙班

English alias

FT-0686944 | SCHEMBL118023 | 1H-PYRAZOLO(3,4-C)PYRIDINE-3-CARBOXAMIDE, 4,5,6,7-TETRAHYDRO-1-( 4-METHOXYPHENYL)-7-OXO-6-(4-(2-OXO-1-PIPERIDINYL)PHENYL)- | 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridine-3-

CAS number

503612-47-3

molecular formula

C25H25N5O4

molecular weight

459.51 g/mol

Exact mass

PSA

111.000 Å²

Logp

2.2

Technical Documents

503612-47-3 | Apixaban.pdf
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