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Product introduction

Afatinib (BIBW2992) is an irreversible EGFR/Neu inhibitor with an IC50 of 14 nM. Afatinib is a potent inhibitor of EGFR phosphorylation. Afatinib showed positive results in assays against a variety of human cancer cell lines, including A431, murine NIH-3T3 cells, and breast cancer cell line BT-474.An irreversible and potent EGFR/Neu inhibitor, inhibits EGFR phosphorylation Afatinib (BIBW2992) is an irreversible EGFR/Neu inhibitor with an IC50 of 14 nM. Afatinib is a potent inhibitor of EGFR phosphorylation. Afatinib showed positive results in assays against a variety of human cancer cell lines, including A431, murine NIH-3T3 cells, and breast cancer cell line BT-474. An irreversible and potent EGFR/Neu inhibitor, inhibits EGFR phosphorylation

Specs ⸢ View details ⸥

Chinese name

阿法替尼

English name

Afatinib

Chinese alias

阿法替尼

English alias

CAS number

439081-18-2

molecular formula

C24H25ClFN5O3

molecular weight

485.94 g/mol

Exact mass

≥95%

PSA

88.600 Å²

Logp

3.600

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