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Product introduction
AF-353 (Ro-4) 是一种有效的、选择性的和口服生物利用的 P2X3 receptor 和 P2X2/3 receptor 的拮抗剂,对人P2X3、大鼠P2X3和人P2X2/3的pIC50值分别为8.06、8.05和7.41。 Information AF-353 AF-353 (Ro-4) is a potent, selective and orally bioavailable antagonist of P2X3 receptor and P2X2/3 receptor with pIC50 of 8.06, 8.05 and 7.41 for human P2X3, rat P2X3 and human P2X2/3, respectively. Targets hP2X3 (Cell-free assay); rP2X3 (Cell-free assay); hP2X2/3 (Cell-free assay) 8.06(pIC50); 8.05(pIC50); 7.41(pIC50)
Chinese name
AF-353, P2X3 拮抗剂
English name
AF-353
Chinese alias
-
English alias
5-[5-Iodo-4-methoxy-2-(propan-2-yl)phenoxy]pyrimidine-2,4-diamine | 2,4-Pyrimidinediamine, 5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]- | GTPL4125 | S0405 | BDBM50257636 | F0516 | SS-4681 | AKOS026750345 | (4-(morpholinomethyl)pbenyl)boronic acid | AF-3
CAS number
865305-30-2
molecular formula
C14H17IN4O2
molecular weight
400.21 g/mol
Exact mass
-
PSA
96.300 Ų
Logp
2.934
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AF-353, P2X3 antagonist 1ml

AF-353, P2X3 antagonist 1ml; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1ml.

item number:A426439-1ml
Product model:1ml
level: 1ml
Lead Time:30days
sold 803 Items
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Specifications:

1ml

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