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Product introduction

AOH1160 is a potent, first-in-class, orally available small molecule proliferating cell nuclear antigen ( PCNA ) inhibitor, interferes with DNA replication, blocks homologous recombination-mediated DNA repair, causes cell-cycle arrest and induces apoptosis . AOH1160 selectively kills many types of cancer cells (mean GI 50 =330 nM) without causing significant toxicity to a broad range of nonmalignant cells Form:Solid IC50& Target:IC50: PCNA

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Chinese name

AOH1160

English name

AOH1160

Chinese alias

English alias

CAS number

2089314-57-6

molecular formula

C25H20N2O3

molecular weight

396.44 g/mol

Exact mass

≥99%

PSA

Logp

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