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Product introduction
AZD4547是一种新型选择性的FGFR抑制剂,靶向作用于FGFR1/2/3,IC50为0.2 nM/2.5 nM/1.8 nM,对FGFR4, VEGFR2(KDR)具有微弱的作用活性,对IGFR, CDK2和p38几乎没有作用活性。Phase 2/3。A novel selective FGFR inhibitor targeting FGFR1, FGFR2, and FGFR3. AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM, weaker activity against FGFR4, VEGFR2(KDR), and little activity observed against IGFR, CDK2, and p38. Phase 2/3. A novel selective FGFR inhibitor targeting FGFR1, FGFR2, and FGFR3.
Chinese name
AZD4547,新型FGFR抑制剂, 成纤维细胞生长因子受体 1 抑制剂
English name
AZD4547
Chinese alias
-
English alias
J-000994 | N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]benzamide | NSC799346 | NSC-799346 | AZD 4547 | J-524217 | KB-74810 | MFCD22580423 | NCGC00346713-05 | N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-y
CAS number
1035270-39-3
molecular formula
C26H33N5O3
molecular weight
463.57 g/mol
Exact mass
-
PSA
91.500 Ų
Logp
3.900
Technical Documents
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AZD4547 10mM in DMSO 1ml

AZD4547 10mM in DMSO 1ml Macklin 1035270-39-3, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:A795718-1ml
Product model:1ml
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Lead Time:30days
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