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Product introduction

产品介绍： Navitoclax (ABT-263)是一种有效的Bcl-xL，Bcl-2和Bcl-w抑制剂，无细胞试验中Ki分别为≤0.5 nM，≤1 nM和≤1 nM，但与Mcl-1和A1结合微弱。 Navitoclax (ABT-263) 是有效的 Bcl-2 抑制剂，可与Bcl-xL，Bcl-2， Bcl-w等多种Bcl-2家族蛋白结合，Ki 值小于 1 nM。 Shipped at 4°C. Store at -20°C. Store under desiccating conditions. Product description Navitoclax (ABT-263) is a potent and orally active Bcl-2 family protein inhibitor that binds to multiple anti-apoptotic Bcl-2 family proteins, such as Bcl-xL, Bcl-2 and Bcl-w, with a Ki of less than 1 nM.

Specs ⸢ View details ⸥

Chinese name

ABT-263,小分子Bcl-2家族蛋白抑制剂

English name

ABT-263

Chinese alias

4-[4-[[2-(4-氯苯基)-5,5-二甲基-1-环己烯-1-基]甲基]-1-哌嗪基]-N-[[4-[[((R)-3-(4-吗啉基)-1-[((苯硫基)甲基]丙基]氨基]-3-[((三氟甲基)磺酰基]苯基]磺酰基]苯甲酰胺', | 生根粉263

English alias

Navitoclax | ABT263 | (R)-4-(4-((4'-Chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide

CAS number

923564-51-6

molecular formula

C47H55ClF3N5O6S3

molecular weight

974.61 g/mol

Exact mass

≥98%

PSA

170.000 Å²

Logp

9.6

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ABT-263 10mM in DMSO 1ml

Name: ABT-263 10mM in DMSO 1ml
Brand: 麦克林
SKU: A798067-1ml

ABT-263 10mM in DMSO 1ml Macklin 923564-51-6, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number：A798067-1ml

Product model：1ml

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Lead Time：30days

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ABT-263 10mM in DMSO 1ml

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