Apimostinel (NRX-1074; AGN-241660) is an orally active NMDA receptor partial agonist. In Vitro Apimostinel (NRX-1074) modulates the NMDA receptor in a similar fashion to GLYX-13, but has a synthetic modification to one of the amino acids, conferring increased potency and oral bioavailability. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo In preclinical models the two compounds both appear to be highly efficacious across a number of CNS disorders . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid