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Product introduction
AMG PERK 44 是一种口服有效的,高选择性的 PERK 抑制剂,IC50 为 6 nM。AMG PERK 44 对 PERK 的选择性分别是 GCN2 (IC50=7300 nM) 和 B-Raf (IC50 >1000 nM) 的 1000 倍和 160 倍。AMG PERK 44 可以诱导自噬 (autophagy)。 AMG PERK 44 is an orally effective, highly selective PERK inhibitor with an IC50 of 6 nM. The selectivity of AMG PERK 44 for PERK is 1000 and 160 times higher than that of GCN2 (IC50=7300 nM) and B-Raf (IC50>1000 nM), respectively. AMG PERK 44 can induce autophagy.
Chinese name
AMG PERK 44,PERK抑制剂
English name
AMG PERK 44
Chinese alias
4-[2-氨基-4-甲基-3-(2-甲基-6-喹啉基)苯甲酰基] -1,2-二氢-1-甲基-2,5-二苯基-3H-吡唑-3-盐酸盐
English alias
4-[2-Amino-4-methyl-3-(2-methyl-6-quinolinyl)benzoyl]-1,2-dihydro-1-methyl-2,5-diphenyl-3H-pyrazol-3-one hydrochloride
CAS number
1883548-84-2
molecular formula
C34H28N4O2•HCl
molecular weight
561.07 g/mol
Exact mass
≥95%
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AMG PERK 44 99% 1mg

AMG PERK 44 99% 1mg CAS 1883548-84-2, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:A936875-1mg
Product model:1mg
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Lead Time:30days
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